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The dermatologist's professional strength brand of choice for your skin


Growth Factor Serum

Professional Strength

  • $69.99 1.0 oz / 30 ml

  • Availability: In Stock
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Product Overview

Innovative and technologically advanced, Replexagen provides unparalleled anti-aging results for damaged, mature skin. Combining potent, clinically proven peptides and five growth factors that are identical in molecular structure to those in the human placenta, the fast-acting Replexagen formula is highly effective in reversing skin damage caused by external elements and the natural aging process. When applied on a regular basis, Replexagen fortifies the skin structure, improving resiliency and offering ongoing anti-aging protection; by supporting the production of the essential protein collagen, delicate, vulnerable skin tissue receives optimal nourishment, resulting in a firmer, wrinkle-free, fully revitalized complexion. In clinical testing, Replexagen’s pharmaceutical-strength key ingredients boosted levels of moisture in the skin by 83% with a single application; after 4 weeks of use, there was a 21% improvement in signs of aging around the eyes. Rich in potent antioxidants that provide ongoing cellular protection against destructive free radicals, Replexagen produces skin that is soft, smooth and glowing with health at any age.

Cosmetic Dermatology

Discover Solvaderm's Professional Strength Products For Healthier And More Beautiful Skin.

Cosmetic Dermatology

Discover Solvaderm's Professional Strength Products For Healthier And More Beautiful Skin.

Replexagen’s revolutionary formula combines powerful peptides with key active nutrients to heal, protect and replenish mature skin. With a synergistic action that enhances its anti-aging benefits, the Replexagen formula reduces the appearance of fine lines and wrinkles, combats dryness and revitalizes dull, tired skin. With consistent use, Replexagen will:
  • Improve the skin structure, making it stronger, more resilient and less susceptible to damage from external and internal stressors
  • Increase cell regeneration, promote healing and support the production of elasticity through the use of essential growth factors
  • Boost antioxidant levels to eradicate damaging free radicals and increase cellular longevity
  • Reduce areas of dry, rough skin, increasing moisture levels by 83% after just one use
  • Support a healthier circulatory system and strengthen skin capillaries for a complexion that is visibly brighter and more radiant
  • Provide ongoing support for the long-term health of the skin by reinforcing the connective tissue
  • Strengthen the skin’s own defense system to radically slow deterioration and protect against further damage

Purified Water, Glycerin, Acetyl Glutamine, Lecithin, sh-Oligopeptide-1, sh-Oligopeptide-2, sh-Polypeptide-1, sh-Polypeptide-9, sh-Polypeptide-11, Bacillus/Soybean/Folic Acid Ferment Extract, 3-Aminopropane Sulfonic Acid, Calcium Hydroxymethionine, Acetyl Hexapeptide-30, Acetyl Hexapeptide-8, Sodium Hyaluronate, Ammonium Acryloyldimethyltaurate/VP Copolymer, Caprylyl Glycol, Polysorbate-20, Pentylene Glycol, Butylene glycol, 1,2-Hexanediol, Arginine, Hydroxyethylcellulose, Phenoxyethanol, Ethylhexylglycerin, Potassium Sorbate.

Biomimetic Peptides

The use of Biomimetic Peptides has revolutionized the anti-aging skincare industry. Essential for slowing the signs of aging in the skin, they are integral to the Replexagen advanced formula and support five important growth factors –

Insulin-like Growth Factor (IGF) – supports the production of skin-firming collagen and reduces numerous signs of aging, particularly in the delicate, vulnerable skin around the eyes.

Epidermal Growth Factor (EGF) – eliminates dry, rough skin by supporting improved levels of hydration, and promotes the creation of healthy new skin cells.

Basic Fibroblast Growth Factor (BFGF) – helps to reduce the severity of blemishes and scarring while improving the skin’s resilience and ability to ward off further signs of aging.

Acidic Fibroblast Growth Factor (AFGF) – creates smoother, plumper, stress-resistant skin through tissue regeneration and cellular revitalization at every level.

Vaso-Endothelial Growth Factor (VEGF) – ensures skin receives optimal amounts of oxygen to maintain long term health, and provides essential nourishment for damaged, aging cells.


With numerous benefits for aging, mature skin, Neuropeptides contained in the Replexagen formula directly affect the way skin cells function. Limiting the movement of facial muscles by inhibiting cellular communication, Neuropeptides give the skin a relaxed appearance, reducing the formation of fine lines and wrinkles especially on the forehead and around the eyes and mouth. Skin appears refreshed, smooth and overall more youthful. Another major benefit of these powerful peptides is their ability to interact with all the active ingredients contained in the Replexagen formula, revitalizing tired skin and significantly slowing the aging process.

Oligo Elements

Oligo Elements are essential for maintaining antioxidant protection against harmful free radicals and optimizing vital enzyme reactions. Additionally, the Oligo Elements found in the powerful Replexagen formula stimulate the production of collagen, thereby boosting the skin’s elasticity, tone and texture. Enhanced levels of this important skin-firming protein result in a plump, smooth complexion and a drastic reduction of sagging, fine lines and surface creases.

Directions Of Use Replexagen

After cleansing and toning the skin, apply a small amount of Replexagen to the skin using the fingertips and massage in with gentle, circular motions until absorbed. For best results, we recommend using Replexagen twice a day, incorporating it into your morning and evening Solvaderm skincare routines.

*Disclaimer: "The FDA has not evaluated these statements and the supplement product is not intended to diagnose, treat, cure or prevent any disease. Remember to read our labels and ingredient lists carefully and follow the appropriate directions for use. If you have a specific allergy or sensitivity, do not use ingredients that may trigger a reaction. An allergy patch test is recommended if there is any doubt or history of skin reactions. Discontinue use if a reaction occurs."

The powerful Replexagen formula works on all areas of the facial skin where signs of aging occur especially those that are prone to developing expression lines such as the forehead, corners of the eyes and around the mouth.

Sources To Support The Claims Made for Replexagen

Penning A [webpage on the Internet] Biomimetics: beauty ingredients that mimic bio functions. GCI Magazine. 2013. Oct 14, [Accessed August 23, 2015]. p. 3.

Varani J, Dame MK, Rittie L, et al. Decreased collagen production in chronologically aged skin: roles of age-dependent alteration in fibroblast function and defective mechanical stimulation. Am J Pathol. 2006;168(6):1861–1868.

Fabi S, Sundaram H. The potential of topical and injectable growth factors and cytokines for skin rejuvenation. Facial Plast Surg. 2014;30(2):157–171

Fitzpatrick RE, Rostan EF. Reversal of photodamage with topical growth factors: a pilot study. J Cosmet Laser Ther. 2003;5(1):25–34.

Schouest JM, Luu TK, Moy RL. Improved texture and appearance of human facial skin after daily topical application of barley produced, synthetic, human-like epidermal growth factor (EGF) serum. J Drugs Dermatol. 2012;11(5):613–62.

Florin L, Maas-Szabowski N, Werner S et al. Increased keratinocyte proliferation by JUN-dependent expression of PTN and SDF-1 in fibroblasts. J Cell Sci 2005; 118: 1981–9.

Kamoun A, Landeau JM, Godeau G et al. Growth stimulation of human skin fibroblasts by elastin-derived peptides. Cell Adhes Commun 1995; 3: 273–81.

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Solvaderm Skincare Your Skin. Our Solutions

At Solvaderm Skincare, we are committed to upholding the highest standards in every aspect of our brand. Since Solvaderm was founded, we've had an unwavering dedication and proven track record of delivering pioneering skincare products.

Recommended and used by dermatologists and skincare professionals world-wide.

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