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Anti-Wrinkle Treatment

Stemuderm is a multi-action anti-wrinkle cream clinically proven to drastically reduce wrinkles, fine lines, and discoloration in just 28 days.

  • Reduces Fine Lines and Wrinkle Depth
  • Plumps the Skin and Boosts Collagen Production
  • Smooths, Firms, Tones & Hydrates The Skin
  • Protects Against Further Damage


Free Standard Shipping is valid in the 48 contiguous United States on any order over $60 after any coupons, promotions, or discounts are applied. Eligible customers must select the Standard Shipping option during checkout in order to receive free shipping. Offer cannot be applied to expedited shipping methods.

Free shipping on orders over $60

Stemuderm Key Benefits

  • Wrinkle Reduction

    Wrinkle Reduction

    Radically reduces the appearance of fine lines and wrinkles around the eyes, forehead, and mouth.

  • Moisturizes


    Rich moisturizers keep your skin hydrated and soft, making it visibly smooth and evenly textured.

  • Firming Effects

    Firming Effects

    Promotes stronger and more supple skin, making it appear dramatically firmer, fuller, and smoother.

Anti-Wrinkle Cream

Stemuderm is a results-driven, professional strength anti-aging solution that effectively combats all visible signs of aging while rejuvenating your skin's elasticity and tone.

This advanced skin-firming complex provides superior results by harnessing powerful peptides and moisturizers that work together in harmony to reduce the appearance of fine lines, wrinkles, age spots and hyperpigmentation, and other surface irregularities while making the skin feel soft and smooth to the touch.

How To Use Stemuderm

Pump small amount of product onto your fingertips and lightly massage into your face, neck, and décolleté, focusing on wrinkles and fine lines.

Natural Ingredients

Solvaderm uses only the most potent, pure, and natural ingredients in our medical-grade skincare products

  • Squalane


    This olive oil-derived extract provides long-lasting hydration, eliminates dryness, improves texture, and diminishes fine lines and wrinkles.

  • Hyaluronic Acid

    Hyaluronic Acid

    Attracts moisture, restoring hydration, eliminating dryness, and plumping the skin to smooth lines. It contains antioxidants that reverse aging.

  • Acetyl-Hexapeptide-8

    Acetyl Hexapeptide-8

    This natural ingredient consists of amino acids that safely decrease muscle contractions under the skin to minimize the appearance of wrinkles and lines.

Additional Ingredients

Jojoba Seed Oil

This deep-penetrating, non-greasy ingredient hydrates and nourishes, improving skin clarity and texture and reducing wrinkles and fine lines.

Acetyl Glutamyl Heptapeptide-1

This peptide relaxes muscles by limiting skin contractions, resulting in reduced wrinkles, furrows, and lines. One article discussed the benefits of this ingredient in anti-wrinkle cosmetic products.

Palmitoyl Oligopeptide

This amino acid compound improves skin elasticity and strength, making it more resistant to stress and damage. It encourages cell matrix repair and renewal and enhances appearance and tone. One review discussed its cosmetic uses and safety.

Malus Domestica Fruit Extract

Malus Domestica Fruit Cell Culture is from a rare Swiss apple, and contains growth enzymes that protect skin cells, increase their longevity, and slow aging. In a 4-week study, 100% of participants had significantly fewer lines and crow's feet.

Apricot Kernel Oil

Apricot Kernel Oil contains fatty acids, vitamins, and antioxidants that seal in moisture and protect against free radicals. It firms and tones the skin, and has soothing anti-inflammatory properties. One study showed its potent antioxidant and antimicrobial benefits.

Matrixyl 3000

This peptide reverses aging by restructuring the skin and stimulating collagen production. It increases elasticity, smoothing lines and wrinkles. One clinical study found that Matrixyl 3000 caused a drastic reduction in wrinkle depth and volume and improved texture.


SYN-AKE™ is an anti-aging tripeptide that relaxes facial muscles to prevent wrinkles and expression lines due to repetitive movements. One study found that SYN-AKE™ increased collagen production and decreased wrinkles and lines.

Stemuderm Customer Reviews